论文部分内容阅读
近十年来,由于对围产保健的重视及手术、麻醉的进展,剖腹产率显著增加。据报道我国剖腹产率平均为9～15％,个别高达20％以上。因此,如何合理应用抗生素,减少剖腹产术后感染发病率,确是一个值得探讨的问题。 20年前,Bruke用动物实验证实,在组织污染后,有一段抗生素能有效地防止原发病灶扩展的有限时间,这段时间大约为3小时。另有人观察到在术前8小时、1小时及术后1～4小时用药或不用药,四组的术后感染率有明显差异。而Ledger认为在手术前1小时,非肠道给予抗生素,一般可使血液中达到足够的水平,而在手术中2～3小时及回病房后再重复给药,前后共3次即可。
In the past decade, due to the emphasis on perinatal health care and surgery, the progress of anesthesia, caesarean section rate increased significantly. It is reported that China’s average caesarean section rate of 9 to 15%, as high as 20% or more. Therefore, how to rationally use antibiotics to reduce the incidence of post-caesarean section infection is indeed a problem worth exploring. Twenty years ago, Bruke used animal experiments to confirm that there was an antibiotic that was effective for preventing a prolonged period of primary tumor expansion after tissue contamination, which was about 3 hours. Another was observed in the preoperative 8 hours, 1 hour and 1 to 4 hours after surgery with or without medication, the four groups of postoperative infection rates were significantly different. However, Ledger believes that one hour before surgery, parenteral administration of antibiotics generally results in a sufficient level of blood, which is repeated 3 to 3 hours after surgery and back to the ward.