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个体发育的各个不同阶段(胎儿→新生儿→婴幼儿→儿童)对药物的反应,在质和量上,与成人不完全相同。处于生长发育中的胎儿和小儿,与成人相比,存在着不少生理、生化学上的差异,因而对药物的吸收、分布、代谢、排泄以及受体敏感性等方面也不同,这些特征是许多药物对不同发育阶段的个体引起付作用的基础。不少无损于儿童和成人的药物,如用于孕妇、乳母或婴儿则可引起药物毒性反应。
The response to drugs at various stages of development (fetus → newborn → infants → children) is not exactly the same in quality and quantity as adults. Fetal and pediatric growth and development, compared with adults, there are many physiological and biochemical differences, and thus the drug absorption, distribution, metabolism, excretion and receptor sensitivity are also different, these features are Many drugs give rise to the basis of pay for individuals at different developmental stages. Many non-destructive drugs for children and adults, such as for pregnant women, nursing mothers or infants can cause drug toxicity.