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引言 早在1909年Maximow就提出干细胞这个概念,他认为在胎儿后期血细胞分化中的淋巴细胞称为“普通干细胞”(Common stemcells)。1961年Till和McCulloch用脾结节实验技术,研究骨髓功能状态,使造血干细胞由概念性阶段进入实验阶段。当时并不知道每个脾结节来源于一个造血干细胞。因此,统称脾结节生成单位(Colony forming
INTRODUCTION As early as 1909, Maximow proposed the concept of stem cells, which he called lymphocytes called “common stem cells” in late fetal hematopoietic differentiation. 1961 Till and McCulloch spleen nodules using experimental techniques to study bone marrow function, so that hematopoietic stem cells from the conceptual phase into the experimental phase. At that time did not know that each spleen nodules from a hematopoietic stem cell. Therefore, collectively referred to as spleen nodule formation unit (Colony forming