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目的探讨梅毒血清学试验甲苯胺红不加热血清试验(TRUST)与梅毒螺旋体抗体明胶颗粒凝集试验(TPPA)在梅毒诊断及治疗中的作用。方法对210例疑为梅毒患者及200例健康体检者的血清作TRUST试验和TPPA试验,并对其结果进行比较分析。结果200例健康体检者中,TRUST试验和TPPA试验均为阴性;210例疑为梅毒患者中,TRUST试验阳性的有192例,TPPA试验阳性的有200例,两者均为阳性的有182例,TPPA试验100%符合临床诊断,TRUST试验有一定的假阳性和假阴性。结论TPPA对TRUST试验阳性病例和疑为梅毒患者有排除和证实作用,而TRUST试验则可作为梅毒患者筛选和疗效观察的一项指标。
Objective To investigate the role of TRUST and TPPA gels in the diagnosis and treatment of syphilis in syphilis serological tests. Methods Serums of 210 suspected syphilis patients and 200 healthy subjects were tested by TRUST and TPPA. The results were compared and analyzed. Results The results of TRUST and TPPA were all negative in 200 healthy subjects. Of the 210 suspected cases of syphilis, there were 192 TRUST positives and 200 TPPA positives, both of which were positive , TPPA test 100% in line with clinical diagnosis, TRUST test has some false positives and false negatives. Conclusion TPPA has the effect of excluding and confirming the positive cases of TRUST and the patients suspected of syphilis, while the TRUST test can be used as an indicator of screening and curative effect of syphilis patients.