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水溶性造影剂应用于胃肠道所引起的腹泻一直被认为是其本身的高渗作用使液体进入肠腔,引起肠腔内压力增加产生牵拉反射而造成肠蠕动增加的结果。但本文实验结果并非如此,而是由于5-羟色胺的释放和胆硷能(Cholinergic)刺激所致。作者用15只狗作了实验,首先观察不同浓度的泛影钠、泛影葡胺及碘酞钠对胃肠道蠕动的作用,然后再观察给予抗胆硷药(阿托品)和/或5-羟色胺抑制剂后各种浓度造影剂对肠张力和运动的影响。结果显示,强高渗的泛影钠(4.8倍于等渗)使小肠的张力和动力明显增强,这种增强在胃排空后仍保持。泛影葡胺与碘酞钠的作用与泛影钠相同。轻度高渗溶液所产生的张力和动力的增加与强高渗溶
Water-soluble contrast agent applied to the gastrointestinal tract caused by diarrhea has been considered as its own hypertonic effect of the liquid into the intestine, causing increased pressure within the intestine produce stretch reflection caused by increased bowel movements results. However, the experimental results in this paper are not so, but due to the release of serotonin and cholinergic stimulation. The experiment was conducted with 15 dogs. First, we observed the effect of different concentrations of pan-sodium, diatrizoate and sodium iodide on gastrointestinal motility, and then observed the effects of anticholinergic drugs (atropine) and / or 5- Effects of Various Concentrations of Contrast Media on Intestinal Tension and Exercise after Serotonin Inhibitors. The results showed that hypertonic sodium pantetrafluoside (4.8 times more isotonic) significantly increased the tension and motility of the small intestine, and this enhancement remained after gastric emptying. Diatrizoate meglumine sodium iodate and the role of the same sodium panamera. Mild hypertonic solution generated by the increase of tension and power and high strength infiltration