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我县用伯氨喹啉进行抗疟疾复发治疗,发生溶血性贫血者4例。患者女,9岁,入院前4天服伯氨喹啉,每天一次,每次11.25毫克基质。第二天有恶心、呕吐,腹痛,头晕。第三天见血水样尿,软弱无力,面色变黄,呼吸速,昏迷15小时而入院。入院检查:体温38.6℃,脉搏160次/分,呼吸56次/分,血压40/0毫米汞柱。发育营养中等,昏迷,唇绀,脉细弱,皮肤、巩膜中度黄染。心、肺正常。肝脾未扪及。化验检查:血红蛋白1.5克%,红细胞69万,白细胞14,100,中性杆状核9%,中性分叶核75%,淋巴14%,酸性1%,网织红细胞
My county with primaquine anti-malarial relapse treatment, hemolytic anemia occurred in 4 cases. The patient, female, 9 years of age, received primaquine 4 days prior to admission once a day for 11.25 mg of substrate. The next day, nausea, vomiting, abdominal pain, dizziness. The third day see blood-like urine, weakness, looking yellow, respiratory rate, coma 15 hours and admitted to hospital. Admission examination: body temperature 38.6 ℃, pulse 160 beats / min, breathing 56 beats / min, blood pressure 40/0 mm Hg. Development of moderate nutrition, coma, cyanosis, pulse weak, skin, sclera moderate yellow dye. Heart, lungs normal. Liver and spleen not palpable. Laboratory tests: 1.5 grams of hemoglobin, erythrocyte 690,000, white blood cells 14,100, 9% of the neutral rod-shaped nucleus, 75% of the neutral leaf core, lymphatic 14%, 1% acid, reticulocytes