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目的探讨青稞提取物对大鼠调节血脂的作用。方法将雄性SD大白鼠根据TC水平随机分为空白对照组、高脂模型对照组和青稞提取物低、中、高3个剂量组,剂量组给予高脂饲料和不同剂量的受试物。30 d后取血,测血清TC、TG、HDL-C三项指标。结果 0.45、1.35 g/kg.bw剂量组的青稞提取物能使大鼠血清中TC、TG降低,与高脂模型对照组比较差异有统计学意义(P<0.05)。结论青稞提取物对大鼠具有降血脂作用。
Objective To investigate the effect of extract of barley on lipid regulation in rats. Methods Male SD rats were randomly divided into three groups according to the level of TC: blank control group, high fat model control group and highland barley extract. The dose group was given high fat diet and different doses of test substance. After 30 d, blood was taken for measurement of serum TC, TG and HDL-C. Results The results showed that the extract of barley wort (0.45,1.35 g / kg.bw) could decrease the content of TC and TG in serum of rats, which was significantly different from that of the control group (P <0.05). Conclusion The extract of barley has a hypolipidemic effect on rats.