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激活素A是转换生长因子β家族中的一员。研究表明,激活素A在细胞增殖、凋亡以及癌变过程中都有重要的调节作用;其中激活素A对具有增殖功能的细胞可诱导其发生凋亡[1]。人的细胞滋养细胞是具有增殖能力的正常细胞,细胞膜上有激活素A受体表达,在妊娠期与激活素A结合,继而影响细胞
Activin A is a member of the transforming growth factor β family. Studies have shown that activin A in cell proliferation, apoptosis and carcinogenesis have an important regulatory role; wherein activin A proliferation of cells can induce its apoptosis [1]. Human cytotrophoblasts are normal cells that have proliferative capacity and have activin A receptor expression on the cell membrane that binds to activin A during pregnancy and subsequently affects cells