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目的通过对巨幼细胞性贫血(MA)的细胞形态学分析总结,为准确诊断 MA 提供形态基础。方法于1999—2005年分析26例 MA 患者的外周血象变化及骨髓中病态红、粒细胞,病态巨核细胞和可染铁的变化。结果 26例患者中,外周血除贫血外,2系减少14例,3系减少8例,骨髓象26例都出现形态学病理改变。结论充分认识 MA 的细胞形态学特征,有助于准确诊断 MA,避免与其他血液病发生混淆。
Objective To summarize the morphological features of megaloblastic anemia (MA) and provide the morphological basis for the accurate diagnosis of MA. Methods In 1999-2005, the changes of peripheral blood and the changes of morbid red, granulocyte, morbid megakaryocytes and iron in bone marrow of 26 patients with MA were analyzed. Results Among the 26 patients, peripheral blood showed 14 cases of 2-line reduction, 8 cases of 3-line reduction, and 26 cases of bone marrow. Conclusion The full understanding of the morphological characteristics of MA may be helpful for the accurate diagnosis of MA and avoid confusion with other hematological diseases.