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[目的]了解张家港市人群乙型肝炎病毒(HBV)感染现状,评价乙肝疫苗纳入儿童免疫策略后的效果。[方法]按《2006年全国人群乙肝等有关疾病血清学调查方案》抽样,开展问卷调查,并采静脉血进行乙肝血清学检测分析。[结果]张家港市人群乙肝疫苗接种率为50.83%,15岁以下人群组乙肝疫苗接种率(99.09%)明显高于15岁以上人群组(2.71%);人群HBsAg阳性率为5.73%,抗-HBs阳性率为52.19%,抗-HBc阳性率为24.43%,HBV感染率为32.43%,HBV感染标志全阴率为37.25%;15岁以下人群组HBsAg阳性率0.30%明显低于15岁以上人群组的11.14%,农民及文盲的HBsAg阳性率和HBV感染率最高。[结论]张家港市乙肝疫苗纳入儿童计划免疫效果显著,今后应加强以成人乙肝疫苗接种为主的综合防制措施。
[Objective] To understand the status of hepatitis B virus (HBV) infection in Zhangjiagang and evaluate the effect of hepatitis B vaccine in children immunization strategy. [Methods] According to the “National Serological Survey Program on Hepatitis B and Other Related Diseases in 2006”, a questionnaire survey was conducted and venous blood was collected for serological detection and analysis of hepatitis B virus. [Results] The vaccination rate of Hepatitis B vaccine in Zhangjiagang was 50.83%, the vaccination rate of Hepatitis B vaccine (99.09%) in the crowd below 15 years old was significantly higher than that in the population above 15 years old (2.71%). The positive rate of HBsAg in the population was 5.73% The positive rate of anti-HBs was 52.19%, the positive rate of anti-HBc was 24.43%, the rate of HBV infection was 32.43%, and the rate of HBV infection was 37.25%. The positive rate of HBsAg in people under 15 years old was significantly lower than 15 11.14% of the population over the age group, peasants and illiterate HBsAg-positive rate and the highest HBV infection rate. [Conclusion] The planned immunization effect of hepatitis B vaccine in children in Zhangjiagang City is significant. Comprehensive prevention and control measures based on adult hepatitis B vaccination should be strengthened in the future.