下咽部梨状窝鳞癌,因位置隐匿,早期症状不明显,易破忽视,尤其粘膜下型癌更易漏诊或误诊为慢性咽炎等。晚期多因侵犯喉与食道上端,症状重而治疗困难。本文介绍二例晚期梨状窝癌患者采用下咽、全喉、食道切除,咽胃吻合,胃代食道手术方法进行治疗的情况,并对手术步骤作了重点介绍。 The pharynx fossa squamous cell carcinoma of the hypopharynx, because of the hidden position, the early symptoms are not obvious, easy to break neglect, especially submucosal cancer is more likely to miss the diagnosis or misdiagnosed as chronic pharyngitis. Late due to violation of the throat and upper esophagus, the symptoms are severe and difficult to treat. This article describes two patients with advanced piriform sinus cancer treated with hypopharyngeal, total laryngeal, esophagectomy, pharyngeal anastomosis, and gastro-esophageal esophagectomy. The surgical procedures are highlighted.