像人类的Muc3一样,啮齿类动物黏蛋白Muc3是一种细胞膜相关性黏蛋白,它与Muc4(即它的啮齿类动物rMuc4)、Muc12、Muc13和Muc17细胞膜上的黏蛋白相似,有某些共同结构特点。膜性黏蛋白称谓也许用词不当,因为已发现Muc1、Muc4、Muc3可溶性分子存在,这种可溶性分子被认为是来自其羧基末端内mRNA的不同剪接体及(或)蛋白酶切。在人类,Muc1发生羧基末端的蛋白酶切,允许 Like human Muc3, the rodent mucin Muc3 is a membrane-associated mucin that is similar to mucins on Muc4 (ie its rodent rMuc4), Muc12, Muc13 and Muc17 cell membranes and has some in common Structural features. Membrane-like mucin appellations may be misnamed because Muc1, Muc4, Muc3-soluble molecules have been found to be present and these soluble molecules are thought to be cleaved by different spliceosomes and / or proteases from their carboxyl-terminal mRNA. In humans, Muc1 undergoes carboxy-terminal proteolytic cleavage, allowing