近几年来,已见有伤寒并发肝炎及沙门氏菌菌血症期伴肝脏损害的报导。在这些报导中,80～90％的患者经实验室检查,显示肝细胞损害,肝组织活检有形态学改变。伤寒性肝炎的发病机制还不清楚,据推测可能是由其它部位释放的沙门氏菌内毒素由血带入肝脏所致。然而,最新迹象表明,身体的内毒素血症对引起伤寒临床表现并不起着较大作用。反之,观察 In recent years, there have been reports of typhoid fever and hepatitis with Salmonella bacteremia with liver damage. In these reports, 80-90% of patients undergo laboratory tests that show hepatocellular damage and morphological changes in liver biopsies. The pathogenesis of typhoid hepatitis is unclear, and it is speculated that Salmonella endotoxin released from other sites may be caused by the blood being brought into the liver. However, the latest indications are that the body’s endotoxemia does not play a major role in causing the clinical manifestations of typhoid fever. On the contrary, observe