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近年来儿童髓母细胞瘤放疗后生存时间有明显的提高,但长期并发症也随之产生,高能X线的脊柱照射是产生后遗症原因之一。使用电子束照射脊柱和硬脊膜下腔,显著地减少了正常组织的剂量,保护了脊柱的椎体、甲状腺、心脏、性腺等正常组织。但在治疗中应考虑脊突对电子束等剂量曲线的分布的影响。本文介绍实验测量脊突对剂量的衰减,以选择合适的能量,使靶区得到足够的剂量。 脊柱分别来自山羊,小狗和婴儿尸体,尺寸各为(长×宽×高):23×10×6.5cm;23×7×5cm,15×3×2cm。模拟治疗为:将脊柱标本放在
In recent years, the survival time of children with medulloblastoma has been significantly improved after radiotherapy, but long-term complications are also followed. High-energy X-rays are one of the causes of sequelae. The use of electron beams to illuminate the spine and the subdural space significantly reduces the dose of normal tissue and protects the spine’s vertebral body, thyroid, heart, gonads, and other normal tissues. However, the effect of the spinous process on the distribution of the isodose curve of the electron beam should be considered in the treatment. This article describes the experiment to measure the attenuation of the dose by the spinous process to select the appropriate energy so that the target area receives sufficient dose. The spine was derived from goats, puppies and baby carcasses, and the dimensions were (length×width×height): 23×10×6.5 cm; 23×7×5 cm, 15×3×2 cm. Simulated treatment: put spine specimens