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目的:探讨慢性阻塞性肺疾病(慢阻肺)合并呼吸衰竭患者采用适应性支持通气与同步间歇指令通气的临床效果。方法:将92例慢阻肺合并呼吸衰竭患者随机分为对照组与观察组各46例,对照组患者采用同步间歇指令通气方式,观察组患者给予适应性支持通气。结果:观察组患者治疗后的氧分压为(94.5±3.7)mm Hg、二氧化碳分压为(57.4±3.6)mm Hg、呼吸频率为(22.1±4.5)次/min、指令呼吸频率为(14.2±0.5)次/min,通气时间为(13.0±3.2)d,均明显好于对照组,具有统计学意义(P<0.05)。结论:针对慢阻肺合并呼吸衰竭患者采用适应性支持通气可显著改善患者呼吸功能,缩短通气时间,具有良好的临床应用价值。
Objective: To investigate the clinical effects of adaptive support ventilation and synchronized intermittent mandatory ventilation in patients with chronic obstructive pulmonary disease (COPD) complicated with respiratory failure. Methods: Ninety-two patients with chronic obstructive pulmonary disease and respiratory failure were randomly divided into control group and observation group with 46 patients in each group. Patients in control group were treated with synchronized intermittent mandatory ventilation and patients in observation group were given supportive ventilation. Results: The partial pressure of oxygen in the observation group was (94.5 ± 3.7) mm Hg, the partial pressure of carbon dioxide was (57.4 ± 3.6) mm Hg, the respiratory rate was (22.1 ± 4.5) ± 0.5) times / min, ventilation time (13.0 ± 3.2) d, which were significantly better than the control group, with statistical significance (P <0.05). Conclusion: Adopting adaptive support ventilation for patients with COPD and respiratory failure can significantly improve the respiratory function and shorten the ventilation time, which has a good clinical value.