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目的研究急性白血病患者化疗与医院感染的相关性。方法通过前瞻性研究方法,对某三级甲等医院血液中心住院接受化疗急性白血病患者医院感染因素进行研究,分析化疗与感染的相关性。结果本次共调查急性白血病患者994例,发生医院感染的患者277例,医院感染率为27.87%;感例次数306例,例次感染率为30.78%。住院进行化疗患者的感染率(32.34%)明显高于未化疗患者。随着化疗周期的增加,感染发生率逐渐降低。结论加强对化疗早期患者监测,有效降低急性白血病患者医院感染发生率。
Objective To study the correlation between chemotherapy and nosocomial infection in patients with acute leukemia. Methods A prospective study was conducted to investigate the relationship between hospital infection and chemotherapy in patients with chemotherapy-induced acute leukemia in a blood bank of a third-class Hospitals. Results A total of 994 cases of acute leukemia, 277 cases of nosocomial infection and 27.87% of nosocomial infections were investigated. The number of cases was 306 and the rate of nosocomial infection was 30.78%. Infection rate of hospitalized chemotherapy patients (32.34%) was significantly higher than those without chemotherapy. With the increase of chemotherapy cycle, the incidence of infection gradually decreased. Conclusion To strengthen the monitoring of early chemotherapy patients, effectively reduce the incidence of nosocomial infections in patients with acute leukemia.