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目的 :比较十二指肠溃疡和慢性浅表性胃炎 (CSG)患者 2 4h胃内pH值的变化。方法 :选择十二指肠溃疡活动期患者 17例和慢性浅表性胃炎 (CSG)患者 10例。将pH锑电极放置于受试者胃体中 ,然后连于便携式记录仪 (DigitrapperMkⅢ )记录 2 4h胃内pH值的变化 ,记录毕将数据输入计算机用Polygram软件进行分析。结果 :十二指肠溃疡患者组pH≤ 2时间百分比明显高于CSG组 (P <0 0 5 ) ,而pH >4时间百分比则低于CSG组(P <0 0 5 )。十二指肠溃疡患者夜间pH≥ 4的时间和pH平均值明显低于CSG组 (P <0 0 1)。十二指肠溃疡患者缺乏夜间pH≥ 4时 ,其发生夜间上腹疼痛的比率明显高于存在夜间pH≥ 4的患者 (P <0 0 5 )。结论 :十二指肠溃疡患者胃酸水平高于CSG组 ,特别是夜间pH值水平明显降低 ,这可能与十二指肠溃疡患者夜间疼痛有关。
Objective: To compare the changes of gastric pH value in 24 h patients with duodenal ulcer and chronic superficial gastritis (CSG). Methods: 17 patients with active stage of duodenal ulcer and 10 patients with chronic superficial gastritis (CSG) were selected. The pH antimony electrode was placed in the body of the subject and then recorded on a portable recorder (Digitrapper Mk III) for changes of gastric pH within 24 hours. Data was entered into a computer and analyzed by Polygram software. Results: The time percentage of pH ≤ 2 in patients with duodenal ulcer was significantly higher than that in CSG group (P <0.05), while the percentage of time with pH> 4 was lower than that in CSG group (P <0 05). Patients with duodenal ulcer at night pH ≥ 4 time and pH was significantly lower than the CSG group (P <0.01). Patients with duodenal ulcer lacking overnight nighttime pH ≥ 4 had a significantly higher incidence of late-night upper abdominal pain than those with nighttime pH ≥4 (P <0.05). Conclusion: The gastric acid level of patients with duodenal ulcer is higher than that of CSG group, especially the nighttime pH value is obviously decreased, which may be related to nocturnal pain in patients with duodenal ulcer.