糖尿病性眼部病变是糖尿病最常见的并发症,是引起视力障碍和失明的重要原因,治疗上也很棘手。为了有效地防治这类并发症,在病因研究中已提出很多理论假说。其中,有关山梨醇通路与糖尿病并发症的关系的理论,受到不少学者的重视。本文将概述近年来在这方面的研究进展。 Diabetic eye disease is the most common complication of diabetes, is an important cause of visual impairment and blindness, the treatment is also very difficult. In order to effectively prevent such complications, a lot of theoretical hypotheses have been proposed in the etiological research. Among them, the theory about the relationship between sorbitol pathway and diabetic complications has attracted the attention of many scholars. This article will outline the research progress in this area in recent years.