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依那普利和赖诺普利为血管紧张素转换酶抑制剂。本文介绍了用时程分辨的荧光测定仪,采用固相免疫分析方法(TRHIA)测定它们在血浆中的含量。根据免疫竞争原理使药物和标记生物素药物竞争有限量抗体,然后加入标记铭的抗生蛋白链菌素(对生物素有特异性)和已结合到固相抗体上
Enalapril and Lisinopril are angiotensin-converting enzyme inhibitors. This article describes the use of time-resolved fluorescence detector, using solid-phase immunoassay (TRHIA) determination of their content in the plasma. The drug and the labeled biotin drug compete for a limited amount of antibody based on the principle of immunological competition, followed by addition of the labeled mAb (specific for biotin) and binding to the immobilized antibody