作者报道了一个大家系反复发生孕早期流产与t(1;20)(p36;p11)相互易位有关。在此家系中有12对夫妻发生两次以上孕早期流产,其中仅1对(两次流产)为正常核型,其余11对夫妻中均有1个为易位携带者,这就清楚地表明反复自然流产与易位之间存在相互关系。另外,易位杂合予比正常个体的后代具有更多的易位杂合子。以前也有作者 The authors report a recurrence of early pregnancy miscarriage in one large family with the relative translocation of t (1; 20) (p36; p11). In this pedigree, there were 12 couples with more than two pregnancies in their first trimester, of whom only 1 (with two abortions) had normal karyotypes and 1 of the remaining couples with translocations, clearly demonstrating There is a correlation between repeated spontaneous abortion and translocation. In addition, translocations have more translocations than offspring of normal individuals. There were also authors before