图形适应被认为仅存在于视觉皮质水平 ,然而本实验室新近实验表明 ,光栅图形适应也存在于正常猫和去视皮质猫的外膝体神经元。本研究目的在于澄清外膝体的图形适应是否来源于视网膜。研究了 79个X和 Y型猫视网膜神经节细胞对长时间的光栅刺激反应。结果显示 :1与外膝体中继细胞不同 ,71 %的神经节细胞对长时间刺激反应不变 ,只有 6%的细胞显示光栅适应 ,而有 2 3%的细胞显示易化作用 ;2上述对长时间的光栅刺激的效应与细胞类型 (X和 Y型或 On-和 Off-中心型 )无关 ;3如同外膝体细胞 ,视网膜神经节细胞的光栅易化作用在刺激后 30 s内结束 ,平均反应幅度上升 1 7% ,其时程符合指数函数 ,平均时间常数为 1 7.7s。本结果提示 ,图形适应可能基本上起源于外膝体 ,而图形易化则起源于视网膜 ,因此外膝体内机制可能导致中继神经元的图形适应 Graphical adaptation is thought to exist only at the visual cortex level, but recent experiments in our laboratory show that grating pattern adaptation is also present in the geniculate bodies of both normal cats and cortical cats. The purpose of this study was to clarify whether the pattern adaptation of the external genicus originates from the retina. A total of 79 X and Y cat retinal ganglion cells were studied for a long time to stimulate the grating. The results showed that: 1 different from the synovial cells, 71% of the ganglion cells respond to long-term stimulation unchanged, only 6% of the cells showed grating adaptation, and 23% of the cells showed facilitation; 2 the above The effect on prolonged grating stimulation was not related to the cell type (X and Y or On- and Off- centered); 3 as with synovial cells, the facilitation of retinal ganglion cells ended within 30 s of stimulation , The average response amplitude increased by 17%. The time-history of the response was in line with the exponential function with an average time constant of 1 7.7s. The results suggest that the pattern of adaptation may have originated mainly in the lateral geniculate body, while the pattern of easy to originate in the retina, so the mechanism of external knee may lead to the adaptation of the relay neurons