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对氯霉素治疗伤寒的估价氯霉素治伤寒已有30年历史,目前在我国一般仍列为首选药物。这主要是氯霉素治疗伤寒能显著的降低伤寒病死率,大大缩短了伤寒热程,减少了肠出血、肠穿孔等严重并发症的发生.但随其临床广泛应用,人们不但发现氯霉素有较多的毒副反应及复发率增高等缺点,近年来还发现有疗效下降的趋势.主要发现为退热时间延长和耐氯霉素菌株出现等问题,使其治疗价值减低.用药后的退热时间,据国外资料报道:1948年平均退
Chloramphenicol on the treatment of typhoid cold chloramphenicol has been 30 years of history, is currently still classified as the preferred drug in our country. This is mainly chloramphenicol treatment of typhoid fever can significantly reduce the mortality of typhoid fever, shorten the typhoid fever, reducing the incidence of intestinal bleeding, intestinal perforation and other serious complications, but with its wide range of clinical applications, people not only found chloramphenicol Have more toxic side effects and higher recurrence rate and other shortcomings in recent years also found a trend of decline in the efficacy of the main findings for the extension of antipyretic and resistant to chloramphenicol strains and other issues, to reduce the value of its treatment after treatment Antipyretic time, according to foreign reports: 1948 average retreat