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目的研究银杏达莫注射液对短暂性脑缺血发作(transient ischemic attack,TIA)患者血液流变学的影响,分析其治疗TIA的机制。方法将82例TIA患者随机分为2组,治疗组42例给予银杏达莫注射液,对照组40例给予复方丹参注射液,14d为一疗程,观察治疗前后及组间血液流变学指标的变化。结果治疗后2组患者血液流变学指标均有改善,治疗组与对照组相比差异有显著性意义,尤其对血小板聚集率的影响更加显著,且治疗过程中未见不良反应。结论银杏达莫注射液能明显改善血液流变学,拮抗血小板的聚集,这是银杏达莫可用于TIA治疗的原因之一。
Objective To study the effect of ginkgo-damo injection on hemorheology in patients with transient ischemic attack (TIA) and analyze the mechanism of its treatment for TIA. Methods Twenty-two patients with TIA were randomly divided into two groups. 42 patients in the treatment group were given gingko damo injection, 40 patients in the control group were given compound salvia miltiorrhiza injection, and 14 days were a course of treatment. Observe the hemorheological parameters before and after treatment and between groups. Variety. Results The hemorheology indexes of both groups improved after treatment. There was significant difference between the treatment group and the control group, especially the platelet aggregation rate, and no adverse reactions were observed during the treatment. Conclusion Ginkgo Damo injection can significantly improve hemorheology and antagonize platelet aggregation. This is one of the reasons why Ginkgo biloba and Damo can be used for TIA treatment.