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目的探讨复方玄驹胶囊联合十一酸睾酮治疗勃起功能障碍(ED)的临床疗效。方法选取本院泌尿外科门诊就诊ED患者112例,按IIEF-5评分为轻、中和重三个层次的患者随机再分为治疗组(轻度19例,中度22例,重度15例)和对照组(轻度18例,中度23例,重度15例)。治疗组和对照组各56例,分别接受复方玄驹胶囊联合十一酸睾酮和十一酸睾酮单药治疗,以IIEF-5评分评价治疗6周两组的疗效及其组间差异。结果治疗6周后的IIEF-5评分结果显示,患者评分均显著提升,且治疗组轻度和中度患者IIEF-5评分相比对应对照组改善更为显著(P<0.05),但重度患者组间差异无统计学意义。治疗组总体疗效明显好于对照组,差异有统计学意义(P<0.05)。结论复方玄驹胶囊联合十一酸睾酮治疗男性ED疗效好于十一酸睾酮单药治疗。
Objective To investigate the clinical efficacy of compound Xuanju Capsule combined with testosterone undecanoate in the treatment of erectile dysfunction (ED). Methods A total of 112 ED patients were selected from our urology clinic. Patients with mild, moderate and severe IIEF-5 scores were randomly divided into treatment group (mild 19, moderate 22, severe 15) And control group (18 mild, 23 moderate, 15 severe). The treatment group and the control group, 56 cases, respectively, to receive compound Xuanju Capsule testosterone undecanoate and testosterone undecanoate monotherapy, IIEF-5 score evaluation of the efficacy of six weeks of treatment and the difference between the two groups. Results The results of IIEF-5 after 6 weeks of treatment showed that the score of patients increased significantly, and the IIEF-5 score of mild and moderate patients in treatment group improved more significantly than that of control group (P <0.05) No significant difference between groups. The overall effect of the treatment group was significantly better than the control group, the difference was statistically significant (P <0.05). Conclusion Compound Xuanju Capsule combined with testosterone undecanoate in male patients with ED better than testosterone undecanoate monotherapy.