论文部分内容阅读
Met为一种表达于上皮细胞和内皮细胞表面的受体酪氨酸激酶,可被其配体肝细胞生长因子(hepatocyte growth factor,HGF)激活,并在肿瘤细胞的生长、增殖、侵袭及抑制细胞凋亡方面发挥重要作用。现已发现,多种肿瘤中均存在Met/HGF信号通
Met, a receptor tyrosine kinase expressed on the surface of epithelial cells and endothelial cells, is activated by its ligand, hepatocyte growth factor (HGF), and is involved in the growth, proliferation, invasion and inhibition of tumor cells Apoptosis plays an important role. It has been found that Met / HGF signaling exists in many tumors