钠洛酮(Naloxone,NX)为羟二氢吗啡酮的衍生物,是阿片受体拮抗剂,1960年合成,1963年始用于临床,对麻醉剂、镇静药有特异性拮抗作用。近年来,随着临床药理学的研究深入,该药在临床上的应用逐渐拓宽,如用于各种中毒、麻醉药过量、心衰、休克、外伤等各种应激状态,以及脑梗塞、眩晕、呼吸衰竭(RF)等。本文仅阐 Naloxone (NX), a derivative of hydroxyhydromorphone, is an opioid receptor antagonist synthesized in 1960 and used in clinical practice since 1963. It has specific antagonistic effects on anesthetics and sedatives. In recent years, with the deepening of clinical pharmacology research, the clinical application of the drug gradually broadened, such as for a variety of poisoning, overdose of anesthesia, heart failure, shock, trauma and other stress states, as well as cerebral infarction, Dizziness, respiratory failure (RF) and the like. This article only illustrates