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[目的]探讨过期麻疹疫苗治疗水痘的效果。[方法]将91例水痘患儿随机分两组,试验组(n=46)给予过期麻疹疫苗三角肌皮下注射,对照组(n=45)给予VitB12肌肉注射,其他治疗相同。观察退热和病程。[结果]试验组退热时间为(1.19±0.30)d,病程为(1.82±0.74)d;对照组退热时间为(2.43±0.94)d,病程为(4.55±1.18)d。两组差异有统计学意义(P﹤0.01)。两组均未发现明显的毒副作用。[结论]过期麻疹疫苗能抑制水痘-带状疱疹病毒的复制,缩短水痘病程,提高治愈率。
[Objective] To investigate the effect of expired measles vaccine on chickenpox. [Method] Ninety-one children with chickenpox were randomly divided into two groups. The experimental group (n = 46) was given hypodermic hypodermic injection of measles vaccine. The control group (n = 45) was injected with VitB12 intramuscularly. The other treatments were the same. Observation of fever and duration. [Results] The duration of fever was (1.19 ± 0.30) days in experimental group and (1.82 ± 0.74) days in experimental group. The duration of fever was (2.43 ± 0.94) days in control group and (4.55 ± 1.18) days in control group. The difference between the two groups was statistically significant (P <0.01). No obvious side effects were found in both groups. [Conclusion] Expired measles vaccine can inhibit the replication of varicella - zoster virus, shorten the course of varicella and improve the cure rate.