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p5 3是一种广谱的肿瘤抑制基因 ,其新家族成员 p5 1具有同 p5 3相似的 DNA结合特性和相似的功能 ,同样可以转录激活 p5 3基因的内源性靶分子 ,如细胞周期抑制基因 p2 1、导致细胞凋亡和生长受抑。本文阐述了它的研究进展
p5 3 is a broad-spectrum tumor suppressor gene. Its new family member p5 1 has similar DNA binding properties and similar functions as p5 3. It also transcriptionally activates endogenous target molecules of the p5 3 gene, such as cell cycle arrest Gene p2 1, leading to apoptosis and growth inhibition. This article describes its research progress