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结肠直肠癌在北美和新西兰是高发区,现发现其发病部位有好发于近端的趋势。作者对北爱尔兰的1.5百万人口中结肠直肠癌的病例进行了研究。病人和方法根据1976～1978年和1990年两个时期登记的结肠直肠癌病例,全部病例都经组织学诊断。把这种肿瘤按其原发部位分为:①组:发生位置近于脾曲者为近端癌;②组:病灶发生在远离脾曲(包括乙状结肠)者为远端癌;③组:直肠癌。对上述2个时期肠癌于肠的发生部位分布差异作统计学分析。
Colorectal cancer is a high-risk area in North America and New Zealand, and it has been found that the site of its onset has a tendency to occur proximally. The authors studied cases of colorectal cancer in 1.5 million people in Northern Ireland. Patients and Methods According to the cases of colorectal cancer registered in 1976-1978 and 1990, all cases were diagnosed by histology. The tumors were divided into their primary sites according to their primary sites: Group 1: proximal sites of splenic lesions were proximal cancers; 2 groups: lesions that occurred distal to splenic flexure (including sigmoid colon) were distal cancers; 3 groups: rectum cancer. The statistical analysis was performed on the differences in distribution of bowel cancer in the above two stages.