Image Features of Retinal Astrocytic Hamartoma in a Patient with Tuberous Sclerosis Complex

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Purpose:.To describe the image features of retinal astrocytic hamartoma in a 35-year-old male patient with tuberous sclerosis complex(TSC).Methods :. Fundus photography,. fundus autofluorescence(FAF), fundus fluorescein angiography(FFA), and spectral domain optical coherence tomography.(SD-OCT).were performed for this retinal astrocytic hamartoma.Results: Fundus photography showed that the retinal astrocytic hamartoma presented as a well-circumscribed,.mulberry-like lesion consisting of glistening yellowish spherules of calcification..FAF demonstrated dense hyper-autofluorescence spots corresponding to retinal astrocytic hamartoma..FFA revealed leakage from dilated retinal capillaries over the hamartoma.SD-OCT indicated moth-eaten optically empty spaces and hyperreflective dots within the lesion..The lesion surface was fluctuate.Conclusion: FAF is a useful imaging modality for obtaining greater contrast between a retinal astrocytic hamartoma and the surrounding retina due to hyper-autofluorescence of calcification in the lesion. FFA is beneficial for monitoring the abnormal blood vessels in these lesions. SD-OCT is capable of visualization the structural details, such as the uneven surface and inner hyperreflective dots. Objective: .To describe the image features of retinal astrocytic hamartoma in a 35-year-old male patient with tuberous sclerosis complex (TSC). Methods:. Fundus photography,. Fundus autofluorescence (FAF), fundus fluorescein angiography Spectral domain optical coherence tomography. (SD-OCT). Were performed for this retinal astrocytic hamartoma. Results: Fundus photography showed that the retinal astrocytic hamartoma presented as a well-circumscribed, .mulberry-like lesion consisting of glistening yellowish spherules of calcification. . FAF demonstrated dense hyper-autofluorescence spots corresponding to retinal astrocytic hamartoma .FFA revealed leakage from dilated retinal capillaries over the hamartoma. SD-OCT indicated moth-eaten optically empty spaces and hyperreflective dots within the lesion. The lesion surface was fluctuate. Conclusion: FAF is a useful imaging modality for greater greater contrast between a retinal astrocytic hamartoma and the surrounding retina due to hyper-auto fluorescence of calcification in the lesion. FFA is beneficial for monitoring the abnormal blood vessels in these lesions. SD-OCT is capable of visualization the structural details, such as the uneven surface and inner hyperreflective dots.
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