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目的 探讨用表阿霉素 (EPI)腹壁下动脉插管化疗联合放疗治疗局部晚期宫颈癌的方法及疗效观察。方法 对 2 0例晚期局限性宫颈癌 ( b期 5例 , b期 15例 )行腹壁下动脉插管化疗联合放疗。对其治疗疗效、毒副反应进行观察及评定。结果 腹壁下动脉插管第 1次化疗后症状缓解率达 95 % ,近期有效率达 80 % ,治疗结束后总有效率为10 0 %。 2 0例均得到随访 ,8例复发 ,其中 1例带瘤生存 ,7例死亡 ;12例健在 ,5年生存率为 6 5 % ,平均生存期为 34月。结论 用 EPI腹壁下动脉插管化疗联合放疗治疗效果好、毒性低 ,是治疗宫颈癌理想的药物及方法
Objective To investigate the efficacy and safety of epirubicin (EPI) combined with intra-abdominal arterial intubation and chemotherapy in the treatment of locally advanced cervical cancer. Methods Twenty cases of locally advanced cervical cancer (5 cases in stage b and 15 cases in stage b) underwent intra-abdominal arterial catheterization combined with radiotherapy. Its curative effect, side effects were observed and evaluated. Results The rate of relieving symptoms was 95% after the first chemotherapy in the inferior abdominal artery, the effective rate was 80% in the short term, and the total effective rate was 100% after the end of the treatment. Twenty cases were followed up and 8 cases relapsed. One case had tumor and 7 cases died. The 12 cases were alive and the 5-year survival rate was 65%. The average survival time was 34 months. Conclusion EPI abdominal artery catheterization chemotherapy combined with radiotherapy has good curative effect and low toxicity, which is the ideal medicine and method for treatment of cervical cancer