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目的:通过对一组157例经组织细胞学检查证实的原发性肝细胞癌患者生存资料及影像学资料的分析,初步研究经导管动脉栓塞(TAE)对不同组织细胞学类型肝细胞癌的治疗效果。材料与方法:8种不同组织细胞学类型的资料较完整的原发性肝细胞癌患者,共计157例,分别接受单纯TAE、单纯手术或TAE+手术切除治疗。对上述病例分别按照不同组织细胞学类型及不同治疗方法进行生存资料和影像学资料分析。结果:本组原发性肝细胞癌的1年、2年、3年和5年的累计生存率分别为74.52%、48.40%、32.48%和11.46%。各组织细胞学类型中,纤维板层型与透明细胞型肝细胞癌的5年生存率分别为25%和29%,。三种治疗方法中,单纯TAE组、单纯手术组与TAE+手术组的平均生存时间分别为25.06(标准误=1.87)、30.38(标准误=2.05)和72.72(标准误=6.90)个月。结论:TAE对不同组织细胞学类型的原发性肝细胞癌在治疗效果上存在差异;本组中,以透明细胞型肝细胞癌对TAE较为敏感,而以小细胞型和低(未)分化型肝细胞癌较不敏感。
OBJECTIVE: To study the survival data and imaging data of 157 cases of primary hepatocellular carcinoma patients confirmed by histological cytology, and to preliminarily study the effects of transcatheter arterial embolization (TAE) on different histological types of hepatocellular carcinoma. treatment effect. Materials and Methods: A total of 157 patients with complete hepatocellular carcinoma with 8 different histological types of cytological data were treated with simple TAE, surgery alone or TAE plus surgical resection. Survival data and imaging data were analyzed for the above cases according to different histological and cytological types and different treatment methods. Results: The cumulative survival rates of primary hepatocellular carcinoma in this group at 1 year, 2 years, 3 years, and 5 years were 74.52%, 48.40%, 32.48%, and 11.46%, respectively. The five-year survival rates of fibrolamellar and clear cell hepatocellular carcinomas were 25% and 29%, respectively, in each tissue cytology type. Among the three treatment methods, the average survival time of simple TAE group, simple surgery group and TAE+ surgery group were 25.06 (standard error = 1.87), 30.38 (standard error = 2.05) and 72.72, respectively. (Standard error = 6.90) months. Conclusions: TAE has different therapeutic effects on different histological types of primary hepatocellular carcinoma; in this group, clear cell type hepatocellular carcinoma is sensitive to TAE, while small cell type and low (un)differentiation. Hepatocellular carcinoma is less sensitive.