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目的探讨潘妥拉唑治疗消化性溃疡的临床疗效。方法对56例HP阳性的消化性溃疡患者随机分为治疗组28例,对照组28例,对照组给予常规治疗+奥美拉唑,对照组,治疗组给予常规治疗+潘妥拉唑,治疗一周后观察症状改善情况,6周后胃镜复查。结果治疗组Hp清除率96%(27/28),明显高于对照组82%(23/28)(P<0.05);治疗组治愈率93%(26/28),对照组治愈89%(25/28),两组无统计学意义(P>0.05)。两组均无严重不良反应。结论潘妥拉唑治愈消化性溃疡有较好疗效,有一定的临床应用价值。
Objective To investigate the clinical efficacy of pantoprazole in the treatment of peptic ulcer. Methods Fifty-six patients with HP-positive peptic ulcer were randomly divided into treatment group (n = 28) and control group (n = 28). The control group was given conventional treatment plus omeprazole, while the control group and treatment group were given conventional treatment plus pantoprazole. A week later to observe the improvement of symptoms, 6 weeks after endoscopy. Results The Hp clearance rate was 96% (27/28) in the treatment group and 82% (23/28) in the control group (P <0.05). The cure rate was 93% (26/28) in the treatment group and 89% in the control group 25/28). There was no significant difference between the two groups (P> 0.05). No serious adverse reactions in both groups. Conclusions There is good curative effect of the treatment of peptic ulcer by the pantoprazole, which has certain clinical value.