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胰岛素抵抗(insulin resistance,IR)是指胰岛素作用的靶组织(肝脏、肌肉和脂肪组织等)对胰岛素的敏感性降低,表现为外周组织对葡萄糖的摄取和利用发生障碍。脂肪组织不仅是一个贮存能量的场所,还是一个活跃的内分泌组织,能分泌一系列激素和细胞因子。其受胰岛素和生长因子的精细调控,维持着机体的内稳态平衡,同时其分泌的脂肪细胞因子反过来作用于机体,调节外周组织对胰岛素的敏感性,参与2型糖尿病胰岛素抵抗的发生发展。本文就脂肪组
Insulin resistance (IR) refers to the insulin sensitivity of target tissues (liver, muscle and adipose tissue, etc.) that is reduced by insulin action, which shows that the peripheral tissues have obstacles to the uptake and utilization of glucose. Adipose tissue is not only a place to store energy, but also an active endocrine tissue that secrete a range of hormones and cytokines. Insulin and growth factors by its fine regulation and maintain the body’s homeostasis balance, while its secretion of adipocytokines in turn act on the body, regulating the peripheral tissue of insulin sensitivity, involved in the development of type 2 diabetes insulin resistance . This article on the fat group