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[目的]探讨腹腔镜胃癌根治手术的安全性、可行性及肿瘤根治性。[方法]选择2005年12月~2010年12月普外科行腹腔镜胃癌D2根治术35例为腹腔镜组,并选择同期开腹胃癌根治术40例为对照组,比较两组手术相关指标、肿瘤根治性指标及术后随访患者的生存率。[结果]腹腔镜组手术时间较对照组长,术中出血量较对照组少,切口长度较对照组短,差异具有统计学意义(均P﹤0.05);腹腔镜组术后排气时间、首次进流质时间及术后住院时间明显较对照组缩短(P﹤0.05),两组总并发症发生率比较差异无统计学意义(P﹥0.05);腹腔镜组肿瘤根治性指标淋巴结清扫数目、近远端切缘距离及1、3、5年生存率均与对照组差异无统计学意义(P﹥0.05)。[结论]腹腔镜胃癌D2根治术是安全、可行的,能达到与开腹根治性全胃切除术相同的肿瘤根治性,且比开腹手术更具微创优势。
[Objective] To investigate the safety, feasibility and radical cure of laparoscopic radical gastrectomy. [Methods] From December 2005 to December 2010, 35 cases of laparoscopic radical gastrectomy for laparoscopic gastric cancer in laparoscopic group and 40 cases of open radical gastrectomy as control group were enrolled in this study. The related indexes of the two groups were compared, Tumor radical index and survival rate of patients after follow-up. [Results] The operation time of laparoscopic group was shorter than that of control group. The amount of bleeding during operation was less than that of control group. The length of incision was shorter than that of control group (all P <0.05) The time of the first admission and the length of stay in the hospital were significantly shorter than those in the control group (P <0.05). There was no significant difference in the incidence of total complications between the two groups (P> 0.05). The number of lymph node dissection, There was no significant difference between the proximal and distal incisal margins and the 1,3-year and 5-year survival rates (P> 0.05). [Conclusions] D2 laparoscopic radical gastrectomy is safe and feasible, and can achieve the same radical tumor curative effect as radical gastrectomy. It is more minimally invasive than laparotomy.