卡培他滨(capecitabine)是一种口服氟尿嘧啶(5-FU)前体药物,可用于治疗结直肠癌和乳腺癌。华法林(warfarin)是目前广泛应用的香豆素类口服抗凝药,用于预防和治疗深静脉血栓、肺栓塞、心脏瓣膜置换术及心房颤动导致的血栓形成,降低心肌梗死复发及心肌梗死后血栓栓塞死亡的危险[1]。但华法林与许多药物或食物同时服用都会产生不良相互作用,不仅影响华法林的抗 Capecitabine is an oral fluorouracil (5-FU) prodrug that can be used in the treatment of colorectal and breast cancer. Warfarin, the widely used coumarin oral anticoagulant, is used to prevent and treat thrombosis caused by deep venous thrombosis, pulmonary embolism, heart valve replacement and atrial fibrillation, to reduce the recurrence of myocardial infarction and myocardial Risk of death from thromboembolism after infarction [1]. However, warfarin and many medications or food taken at the same time will have adverse interactions, not only affect the anti-warfarin