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甲氨蝶呤 (ＭＴＸ)是继皮质激素之后应用最广泛的抗风湿性疾病药物。已经证实 ,该药对成年风湿病的治疗具有肯定疗效。目前在小儿风湿病中的应用情况也越来越受到关注。本文就ＭＴＸ在小儿风湿性疾病中的应用情况综述如下。1 ＭＴＸ的作用机制和药物动力学特点已经证实 ,治疗?
Methotrexate (MTX) is the most widely used antirheumatic drug following corticosteroids. It has been confirmed that the drug has a positive effect on the treatment of adult rheumatism. Currently in the application of pediatric rheumatism more and more attention. This article reviews the use of MTX in pediatric rheumatic diseases as follows. 1 MTX mechanism of action and pharmacokinetic characteristics have been confirmed, treatment?