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随着肥胖患者的日益增多,2型糖尿病患病率也有增高的趋势,严重影响了人们的健康和生活质量。2型糖尿病是一种进展性疾病,随着病程进展,血糖逐渐升高,控制高血糖的治疗强度需要随之加强,常需要多种手段间的联合治疗。2型糖尿病的病因和发病机制极为复杂,不同患者还存在着异质性。因此,临床医生不能期望每位患者在服用一种或几种降糖药后都能实现血糖达标。而且,随着疾病进展,医生还需根据患者的自身代谢情况,对药物剂量给予调整,包括胰岛素。
With the increasing number of obese patients, the prevalence of type 2 diabetes also has an increasing trend, seriously affecting people’s health and quality of life. Type 2 diabetes is a progressive disease, with the course of the disease, blood glucose gradually increased, the control of high blood sugar treatment intensity needs to be strengthened, often require a combination of means of treatment. The etiology and pathogenesis of type 2 diabetes is extremely complex, and heterogeneity exists in different patients. Therefore, clinicians can not expect each patient to achieve glycemic compliance after taking one or more hypoglycemic agents. Moreover, as the disease progresses, physicians also need to adjust the dose of medication, including insulin, according to the patient’s own metabolism.