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目的探讨艾迪注射液与125I粒子植入治疗晚期恶性肿瘤的临床疗效。方法对29例晚期恶性肿瘤患者行放射性125Ⅰ粒子肿瘤内植入治疗,植入当天起采用艾迪注射液静脉滴注,每日1次,10 d为1个疗程,治疗1个月后复查,观察治疗前后生活质量和主要症状改善及肿瘤控制情况。结果经综合治疗后86%~93%的患者卡氏评分和体质量稳定或提高;疲乏、纳差、疼痛等主要症状改善;肿瘤控制情况,CR 2例,PR 10例,MR 9例,NC 4例,PD 4例,肿瘤总缩小好转率72%。结论艾迪注射液与125Ⅰ粒子植入治疗对改善晚期恶性肿瘤患者生活质量、控制肿瘤的增长有显著疗效。
Objective To investigate the clinical effects of Aidi Injection and 125I seed implantation in the treatment of advanced malignant tumors. Methods Twenty-nine patients with advanced malignant tumor were treated by 125I radioactive tumor implantation. Aidi injection was administered intravenously once a day for 10 days for one course of treatment. After 1 month of treatment, Before and after treatment to observe the quality of life and the improvement of the main symptoms and tumor control. Results After treatment, 86% -93% of the patients had stable or improved cardiothoracic score and body weight; the main symptoms such as fatigue, anorexia and pain were improved; the tumor control was CR 2, PR 10, MR 9, NC 4 cases, PD 4 cases, the total tumor reduction rate of 72% improvement. Conclusion Aidi injection and 125 Ⅰ seed implantation can improve the quality of life of patients with advanced malignant tumor and control the growth of tumor significantly.