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肾上腺糖皮质类固醇(以下简称激素)应用于感染性疾患已近30余年,由于它具有退热,消炎及改善全身中毒症状的良好作用,故应用比较广泛。由于激素剂型的逐年增多,药效也逐年提高,故深受临床工作者的欢迎,但由激素所诱致的继发感染及并发症,确较前有所增加。由于不少新抗菌素的问世,以及支持疗法的不断改进,故感染性疾病的病死率明显下降,因此对皮质激素的疗效评价,有必要重新加以核实,以便严格掌握其适应症及禁忌症。
Adrenal glucocorticoid (hereinafter referred to as hormone) applied to infectious diseases for nearly 30 years, because of its antipyretics, anti-inflammatory and improve the symptoms of systemic poisoning good effect, it is widely used. As hormone dosage forms increased year by year, the efficacy also increased year by year, it is welcomed by clinicians, but the secondary infection caused by hormones and complications, indeed an increase over the previous. Due to the advent of many new antibiotics, as well as the continuous improvement of supportive therapies, the mortality of infectious diseases has dropped significantly. Therefore, the evaluation of the efficacy of corticosteroids needs to be re-verified in order to strictly control its indications and contraindications.