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强直性脊椎炎与HLA-B27呈高度关联,临床上常利用这一关联鉴别诊断腰腿痛病人。检测HLA-B27的方法已有许多,但各有弱点。本研究目的是想建立一种简便准确的HLA-B27-PCR-SSP分型方法。
Ankylosing spondylitis and HLA-B27 were highly correlated, often associated with the clinical diagnosis of low back pain patients. There are many ways to detect HLA-B27, but each has its own weakness. The purpose of this study is to establish a simple and accurate HLA-B27-PCR-SSP typing method.