脑血管痉挛(CVS)是蛛网膜下腔出血(SAH)最严重的并发症之一,其发生率高达30%~90%,是SAH患者致死致残的主要原因。1951年Ecker及Rei menschneider首先利用造影证明了脑血管痉挛现象的存在,并作了详细的描述,但CVS的发病机制仍未完全阐明,仍存在很多令人难以理解和亟待解决的问题。但有关Rho激酶通路在CVS发生中的作用研究取得了一些进展。现将有关文献综述如 Cerebral vasospasm (CVS) is one of the most serious complications of subarachnoid hemorrhage (SAH), and its incidence is as high as 30% to 90%. It is the main cause of death and disability in patients with SAH. In 1951, Ecker and Rei menschneider firstly used angiography to prove the existence of cerebral vasospasm and gave a detailed description. However, the pathogenesis of CVS has not been fully elucidated and there are still many problems that are difficult to understand and urgently solved. However, some progress has been made on the role of Rho kinase pathway in the pathogenesis of CVS. Now the literature review