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目的和方法转移性肝癌的血液供应除主要来源于肝动脉外亦有门静脉的参于,同时门静脉又是实体肿瘤肝内转移的途径,作者自1992年1月至1995年12月对20例继发性肝癌病人采用经腹行肝动脉和门静脉系统双插管的方法进行介入治疗。结果:8例癌胚抗原(CEA)增高的患者有6例持续下降。根据治疗前后的CT图象对比显示肿瘤缩小者13例,肿瘤缩小28%~72%,平均50%。全组平均生存时间l3.5个月,半年、1年及2年生存率分别为95%、65%和20%。结论:经肝动脉、门静脉双插管介入治疗方法安全、方便,易于推广,其临床治疗效果需进一步提高。
Objectives and methods The blood supply of metastatic liver cancer is not only the hepatic artery but also the portal vein, and the portal vein is also the pathway for intrahepatic metastasis of solid tumors. The authors have studied 20 cases of liver cancer from January 1992 to December 1995. Liver cancer patients underwent transcatheter arterial and portal venous catheterization. RESULTS: Six patients with increased CEA were consistently reduced in 6 cases. According to the comparison of the CT images before and after treatment, there were 13 cases of tumor shrinkage, and tumors were reduced by 28% to 72% with an average of 50%. The average survival time of the whole group was 13.5 months. The half-year, 1-year, and 2-year survival rates were 95%, 65%, and 20%, respectively. Conclusion: The interventional treatment of hepatic artery and portal vein with double cannula is safe, convenient and easy to popularize. The clinical therapeutic effect needs further improvement.