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[目的]分析天津市婴儿麻疹流行状况及相关因素,为控制麻疹提出策略。[方法]对天津市历年法定传染病报告系统麻疹监测数据和流行病学调查资料进行分析,用酶联免疫吸附试验(ELISA)间接法检测麻疹IgG抗体。[结果]天津市麻疹发病显示明显的年龄分布特点,2005~2009年间均是1岁以下婴儿发病率最高,婴儿麻疹占麻疹病例的构成比呈增高趋势。73.97%的8月龄~1岁婴儿麻疹病例未进行过免疫接种。8月龄以下婴儿随月龄增长抗体阳性率逐渐下降,7月龄时抗体阳性率降至16.67%。医院就诊史与1岁以下婴儿麻疹有关,OR=15.4。[结论]天津市2005~2009年间麻疹发病均是1岁以下婴儿发病率最高,婴儿麻疹占麻疹病例的构成比呈增高趋势。未及时免疫、麻疹胎传抗体的滴度低以及医院就诊史等因素可能与婴儿麻疹发病有关。
[Objective] To analyze the epidemic situation of infant measles in Tianjin and its related factors and put forward strategies for controlling measles. [Method] The measles monitoring data and epidemiological survey data of legal notifiable infectious disease reporting system in Tianjin were analyzed. Measles IgG antibody was detected by enzyme - linked immunosorbent assay (ELISA) indirect method. [Results] The incidence of measles in Tianjin showed obvious age distribution. The incidence of measles among infants was highest in infants under 1 year of age from 2005 to 2009. 73.97% of measles cases aged 8 months to 1 year old were not immunized. The positive rate of antibody with increasing age of the infants under 8 months of age gradually decreased, and the positive rate of antibody decreased to 16.67% at 7 months of age. The history of hospital visits was related to infant measles under 1 year of age, OR = 15.4. [Conclusion] The incidence of measles in Tianjin from 2005 to 2009 was the highest among infants less than 1 year old, and the proportion of measles to measles in infants increased. Not timely immunization, measles measles low antibody titers and history of hospital visits and other factors may be related to the incidence of infant measles.