本文观察了64例麻疹患儿急性期的T淋巴细胞亚群、红细胞免疫和免疫球蛋白的变化,结果患儿的成熟T细胞(CD_3~+)、辅助/诱导T细胞(CD_4~+)明显降低,杀伤/抑制性T细胞(CD_8~+)增高;红细胞免疫中,患儿的免疫复合物花环率增高,C3b受体花环率降低;免疫球蛋白水平无明显变化。分析发现,麻疹患儿急性期免疫功能的降低以细胞免疫为主。64例患儿中12例有麻疹疫苗接种史,其临床表现较轻,但与无麻疹疫苗接种史的患儿比较,所测免疫学指标无明显差异。 In this study, we observed the changes of T lymphocyte subsets, erythrocyte immunoglobulin and immunoglobulin in 64 cases of measles children in acute phase. Results The percentage of CD_3 ~ + and CD_4 ~ + in children with measles were significantly higher (CD_8 ~ +) increased. In erythrocyte immunity, the rate of rosette of immunocomplex in children increased and the rate of C3b rosette decreased. There was no significant change in immunoglobulin levels. Analysis found that measles children with reduced immune function in the acute phase of cellular immunity based. Among the 64 children, 12 had measles vaccination history, and their clinical manifestations were mild. However, there was no significant difference in immunological indexes between the children with measles vaccination history and those without measles vaccination history.