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抗精神病药物致癫痫25例中,男11例,女14例;年龄16～42岁,平均24.6岁。诊断:精神分裂症22例,分裂情感性精神病3例。既往有脑外伤,脑炎史3例。 1.服药种类、剂量、时间与癫痫发作关系:氯氮平14例、癫痫出现时药量75～600mg/d,平均450mg/d,服药1～54天,平均18天;氯丙嗪4例,剂量225～650mg/d,平均431mg/d,服药5～64天,平均26天;丙咪嗪3例,剂量150～250mg/d,平均200mg/d,服药10～21天,平均16天;泰尔登2例,剂量均为500mg/d,分别服药13及15天;奋乃静1例,剂量36mg/d,服药25天;阿密替林1例,剂量300mg/d,服药14天。
25 cases of antipsychotic epilepsy, 11 males and 14 females; aged 16 to 42 years, mean 24.6 years old. Diagnosis: schizophrenia in 22 cases, schizoaffective psychosis in 3 cases. Past traumatic brain injury, encephalitis in 3 cases. 1. The medication type, dose, time and epileptic seizures: clozapine in 14 cases, epilepsy when the dose of 75 ~ 600mg / d, an average of 450mg / d, taking 1 to 54 days, an average of 18 days; 4 cases of chlorpromazine , Dose 225 ~ 650mg / d, an average of 431mg / d, taking 5 to 64 days, an average of 26 days; imipramine 3 cases, the dose of 150 ~ 250mg / d, average 200mg / d, taking 10 to 21 days, an average of 16 days ; Tier Deng 2 cases, the dose was 500mg / d, respectively, taking 13 and 15 days; perphenazine 1 case, a dose of 36mg / d, taking 25 days; amitriptyline in 1 case, a dose of 300mg / d, taking 14 day.