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目的:探讨艾滋病(AIDS)患者宫颈分泌物淋病奈瑟菌(NG)、解脲支原体(UU)、沙眼衣原体(CT)检测结果及与CD~(4+)T细胞计数和HIV载量的关系。方法:检测35例AIDS患者NG、UU、CT、CD~(4+)T细胞计数和HIV载量,并比较NG、UU、CT在不同CD~(4+)T细胞计数(<50/mm~3、50~199/mm~3、200~349/mm~3、≥350/mm~3)及HIV载量(<1000 copy/ml、1000~4999 copy/ml、5000~9999 copy/ml、≥10000 copy/ml)中阳性与阴性患者的构成比。结果:35例AIDS患者的宫颈分泌物NG、UU和CT检测阳性分别为6例(17.1%)、5例(14.3%)和3例(8.6%)。随着CD~(4+)T细胞计数的升高,NG、UU和CT阳性患者的构成比例较阴性患者降低,差异有统计学意义(Z=2.406,Z=2.443,Z=2.252,P<0.05)。随着HIV载量的升高,NG和UU阳性患者的构成比例较阴性患者升高,差异有统计学意义(Z=1.135,Z=2.126,P<0.05);而CT阳性患者的构成比例与阴性患者比较,差异无统计学意义(Z=1.205,P>0.05)。结论:在对低CD~(4+)T细胞计数和高HIV载量的AIDS患者的诊疗中,应当积极检测宫颈分泌物NG、UU和CT,对预防盆腔炎发生有益。
Objective: To investigate the relationship between cervical secretions of Neisseria gonorrhoeae (NG), UU (Ureaplasma urealyticum) and Chlamydia trachomatis (CT) in cervical secretions of patients with AIDS and their relationship with CD 4+ T cell count and HIV load . Methods: The counts of NG, UU, CT, CD 4 + T cells and HIV load were detected in 35 cases of AIDS patients. The levels of NG, UU and CT in different CD 4 T cells (<50 / mm ~ 3,50 ~ 199 / mm ~ 3,200 ~ 349 / mm ~ 3, ≥350 / mm ~ 3) and HIV load (<1000 copy / ml, 1000 ~ 4999 copy / ml, , ≥10000 copy / ml) in patients with positive and negative constituent ratio. Results: The positive rates of NG, UU and CT in cervical secretions from 35 AIDS patients were 6 (17.1%), 5 (14.3%) and 3 (8.6%) respectively. With the increase of CD4 ~ + T cell count, the proportion of NG, UU and CT positive patients was lower than that of negative patients (Z = 2.406, Z = 2.443, Z = 2.252, P < 0.05). With the increase of HIV load, the proportions of NG and UU-positive patients were higher than those of negative patients (Z = 1.135, Z = 2.126, P <0.05) Negative patients, the difference was not statistically significant (Z = 1.205, P> 0.05). Conclusion: In the diagnosis and treatment of AIDS patients with low CD 4+ T cell count and high HIV load, cervical secretions NG, UU and CT should be positively detected, which is beneficial to the prevention of pelvic inflammatory disease.