论文部分内容阅读
子宫内膜异位症(EMs)是一种雌激素依赖性疾病。雌激素与其受体(ER)结合后调节一系列基因的表达而发挥重要的生理作用。因此,ER的变化可能影响雌激素生物学效应。近年研究表明,ER基因多态性与EMs发病存在相关性。研究ER基因多态性与EMs的相关性对揭示EMs的发生、发展过程及治疗、判断预后等具有重要意义。就ER基因多态性与EMs发病相关性做文献综述。
Endometriosis (EMs) is an estrogen-dependent disease. Estrogen binds to its receptor (ER) to regulate the expression of a series of genes and play an important physiological role. Therefore, changes in ER may affect estrogen biological effects. Recent studies have shown that there is a correlation between the ER gene polymorphism and the pathogenesis of EMs. Studying the correlation between ER gene polymorphism and EMs is of great significance to reveal the occurrence, developmental process, treatment and prognosis of EMs. Literature review on the relationship between ER gene polymorphism and the pathogenesis of EMs.