本文报道了氧哌嗪青霉素对临床分离的430株致病菌的体外抗菌活性并与五种头孢菌素作了比较。结果表明氧哌嗪青霉素是一种广谱的半合成青霉素,对革兰阳性球菌及革兰阴性细菌均有良好的抗菌活性。此外,本品对粪链球菌和不动杆菌亦有较好的抗菌活性,而一、二、三代头孢菌素在这方面是很差的 In this paper, the in vitro antibacterial activity of piperacillin against 430 pathogenic bacteria isolated from clinical isolates was reported and compared with five cephalosporins. The results showed that piperacillin penicillin is a broad spectrum of semi-synthetic penicillin, Gram-positive cocci and Gram-negative bacteria have good antibacterial activity. In addition, the product of Streptococcus faecalis and Acinetobacter also have good antibacterial activity, and first, second and third generation cephalosporins in this regard is poor