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本文对52例急性心肌梗塞(AMI)6小时内入院患者进行静脉给药溶解血栓治疗,其溶栓药物为尿激酶(UK)、去纤酶,其中6例并用前列腺素E1(PGE1)联合溶栓。其结果显示:52例中再通29例再通率55.77%。其中UK组36例再通20例,再通率55.56%;UK+PGE1组6例,4例再通,再通率66.67%;去纤酶组10例,再通5例,再通率50.0%。再通表现:梗塞性胸痛明显缓解;抬高ST段明显下降,平均最大下降率72.25±19.25%;CK峰值时间15.1±3.1小时,CK一MB峰值14.8±2.6小时;再灌注心律改变21例,占72.4%。再阻塞9例,占31.03%。住院死亡5例,占9.6%。
In this paper, 52 patients with acute myocardial infarction (AMI) within 6 hours of admission to patients with intravenous thrombolytic therapy, the thrombolytic drugs for urokinase (UK), defibrase, of which 6 cases with prostaglandin E1 (PGE1) bolt. The results showed that: 52 cases of recanalization in 29 cases, the recanalization rate of 55.77%. The UK group of 36 cases recanalization in 20 cases, the recanalization rate of 55.56%; UK + PGE1 group of 6 cases, 4 cases of recanalization, the recanalization rate of 66.67%; defibrase group of 10 cases, and then in 5 cases, and then through Rate of 50.0%. Recanalization showed: infarction chest pain was relieved; elevated ST segment decreased significantly, the average maximum rate of decline of 72.25 ± 19.25%; CK peak time of 15.1 ± 3.1 hours, CK MB peak of 14.8 ± 2.6 hours; reperfusion heart rate changes in 21 cases, accounting for 72.4%. Reocclusion in 9 cases, accounting for 31.03%. Inpatient death in 5 cases, accounting for 9.6%.